Delta-8 Tetrahydrocannabinol is very natural as it is extracted directly from the Cannabis plant itself. The confusion as to whether it is synthetic or not comes into play when there is human involvement in the mass production of THC. If you wonder if it matters if it is synthetic or not, you would have to look at the effects that can be gotten from synthetic cannabinoids. But we do not have to worry as delta-8 THC is entirely safe for consumption.